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  • [Leu5]-Enkephalin

    2025-08-27

    [Leu5]-Enkephalin

    Author: ApexBio

    spu:

    B5214

    CAS:

    58822-25-6

    purity:

    0.9957

    shortsummary:

    An endogenous pentapeptide that acts as an agonist at opioid receptors

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    Formula:

    C28H37N5O7

    M.Wt:

    555.63

    Chemical Name:

    (2S,5R,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-2-isobutyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecan-1-oic acid

    SMILES:

    O=C([C@@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC(C=C2)=CC=C2O)N)=O)=O)=O)N[C@H](C(O)=O)CC(C)C

    Solubility:

    ≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO

    Storage:

    Desiccate at -20°C

    Physical Appearance:

    A solid

    DeliveryTime:

    In stock

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    ShippingType:

    Blue ice

    description:

    [Leu5]-Enkephalin, naturally present in mammalian brain, is one of the endogenous pentapeptides with morphine-like properties. [Leu5]-Enkephalin exhibits agonistic actions at both the δ- and μ-opioid receptors, with substantially greater preference for the former, but shows little effect on the κ-opioid receptor. In humans, the δ-opioid receptor is most heavily expressed in basal ganglia and neocortical regions, and associated with pain, depression, as well as learning and memory. [Leu5]-Enkephalin, along with the other endogenous pentapeptide, [Met5]-enkephalin, have been found to behave as potent, yet short-lived opiates in vivo.

    [Leu5]-Enkephalin PMC10816153

    related websites:

    APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 4682 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.

    https://www.apexbt.com/