[Leu5]-Enkephalin
[Leu5]-Enkephalin
Author: ApexBio
spu:
B5214
CAS:
58822-25-6
purity:
0.9957
shortsummary:
An endogenous pentapeptide that acts as an agonist at opioid receptors
Formula:
C28H37N5O7
M.Wt:
555.63
Chemical Name:
(2S,5R,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-2-isobutyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecan-1-oic acid
SMILES:
O=C([C@@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC(C=C2)=CC=C2O)N)=O)=O)=O)N[C@H](C(O)=O)CC(C)C
Solubility:
≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO
Storage:
Desiccate at -20°C
Physical Appearance:
A solid
DeliveryTime:
In stock
ShippingType:
Blue ice
description:
[Leu5]-Enkephalin, naturally present in mammalian brain, is one of the endogenous pentapeptides with morphine-like properties. [Leu5]-Enkephalin exhibits agonistic actions at both the δ- and μ-opioid receptors, with substantially greater preference for the former, but shows little effect on the κ-opioid receptor. In humans, the δ-opioid receptor is most heavily expressed in basal ganglia and neocortical regions, and associated with pain, depression, as well as learning and memory. [Leu5]-Enkephalin, along with the other endogenous pentapeptide, [Met5]-enkephalin, have been found to behave as potent, yet short-lived opiates in vivo.
[Leu5]-Enkephalin PMC10816153related websites:
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